General Population Cohort (GPC) Publications


GPC Publications

The following publications have been made under the GPC:

Year Authors Title Journal DOI
1991 Seeley J, Wagner HU, Mulemwa J, Kengeya-Kayondo JF, Mulder DW The development of a community based HIV/AIDS service in a rural area of Uganda AIDS Care 10.1080/09540129108253064
1992 Seeley JA, Kengeya-Kayondo JF, Mulder DW Community-based HIV/AIDS research: whither community participation? Unsolved problems in a research programme in rural Uganda Soc Sci Med 10.1016/0277-9536
1993 Nunn AJ, Biryahwaho B, Downing RG, van der Groen G, Ojwiya A, Mulder DW Algorithms for detecting antibodies to HIV-1: results from a rural Ugandan cohort AIDS 10.1097/00002030-199308000-00005
1993 Wagner HU et al. General and HIV-1 associated morbidity in a rural Ugandan community AIDS
1993 Seeley JA Searching for indicators of vulnerability: a study of household coping strategies in rural south west Uganda—a background report: Uganda Virus Research Institute 1993
1993 Seeley JA, Kajura E, Bachengana C, Okongo M, Wagner HU, Mulder DW The extended family and support for people with AIDS in a rural population in south west Uganda: a safety net with holes? AIDS Care 1993;5:117–22 10.1080/09540129308258589
1994 Mulder DW, Nunn A, Wagner HU, Kamali A, Kengeya-Kayondo JF HIV-1 incidence and HIV-1 associated mortality in a rural Ugandan population cohort AIDS 10.1097/00002030-199401000-00013
1994 Nabaitu J, Bachengana C, Seeley J Marital instability in a rural population in south west Uganda: Implication for the spread of HIV-1 infection Africa
1994 Kengeya-Kayondo JF, Seeley JA, Kajura-Bajenja E, et al Recognition, treatment seeking behaviour and perception of cause of malaria among rural women in Uganda Acta Trop 10.1016/0001-706X
1994 Nunn AJ, Kengeya-Kayondo JF, Malamba S, Seeley JA, Mulder DW Risk factors for HIV-1 infection in adults in a rural Ugandan community: a population study AIDS 10.1097/00002030-199401000-00012
1994 Wagner HU, Van Dyck E, Roggen E, et al Seroprevalence and incidence of sexually transmitted diseases in a rural Ugandan Population Int J STD AIDS 10.1177/095646249400500509
1994 Seeley JA, Malamba SS, Nunn AJ, Mulder DW, Kengeya-Kayondo JF, Barton T Socio economic status, gender and risk of HIV-1 infection in a rural community in south west Uganda Med Anthropol Q
1994 Mulder DW, Nunn AJ, Kamali A, Nakiyingi J, Wagner HU, Kengeya-Kayondo JF Two-year HIV-1 associated mortality in a Ugandan rural population Lancet 10.1016/S0140-6736
1995 Mulder D, Nunn A, Kamali A, Kengeya-Kayondo J Decreasing HIV-1 seroprevalence in young adults in a rural Ugandan cohort BMJ 10.1136/bmj.311.7009.833
1995 Kengeya-Kayondo JF, Malamba SS, Nunn AJ, Seeley JA, Ssali A, Mulder DW Human immunodeficiency virus (HIV-1) seropositivity among children in a rural population of south-west Uganda: probable routes of exposure Ann Trop Paediatr 10.1080/02724936.1995.11747758
1995 Nunn AJ, Wagner HU, Kamali A, Kengeya-Kaoyndo JF, Mulder DW Migration and HIV-1 seroprevalence in a rural Ugandan population AIDS
1996 Whitworth J, Pickering H, Morgan D Disclosing HIV status to partners Lancet
1996 Nunn AJ, Mulder DW, Kamali A, Kengeya-Kayondo JF, Whitworth JAG HIV-1 incidence in sub-Sahara Africa Lancet 10.1016/S0140-6736
1996 Kengeya-Kayondo JF, Kamali A, Nunn AJ, Ruberantwari A, Wagner HU, Mulder DW Incidence of HIV-1 infection in adults and sociodemographic characteristics of seroconverters in a rural population in Uganda, 1990–1994 Int J Epidemiol 10.1093/ije/25.5.1077
1996 Mulder DW, Nunn A, Kamali A, Kengeya-Kayondo JF Post-natal incidence of HIV-1 infection among children in a rural Ugandan population: no evidence for transmission other than mother to child Trop Med Int Health 10.1046/j.1365-3156.1996.d01-12.x
1996 Kamali A, Seeley JA, Nunn AJ, Kengeya-Kayondo JF, Ruberantwari A, Mulder DW The orphan problem: experience of a sub-Saharan Africa rural population in the AIDS epidemic AIDS Care 10.1080/09540129650125470
1996 Kamali A, Wagner HU, Nakiyingi J, Sabiiti I, Kengeya-Kayondo JF, Mulder DW Verbal autopsy as a tool for diagnosing HIV-related adult deaths in rural Uganda Int J Epidemiol 10.1093/ije/25.3.679
1997 Carpenter LM, Nakiyingi JS, Ruberantwari A, Malamba SS, Kamali A, Whitworth JAG Estimates of the impact of HIV infection on fertility in a rural Ugandan population cohort Health Transition Rev
1997 Nunn AJ, Mulder DW, Kamali A, Ruberantwari A, Kengeya-Kayondo JF, Whitworth J Mortality associated with HIV-infection over five years in a rural Ugandan population: a cohort study BMJ 10.1136/bmj.315.7111.767
1999 Kamali A, Whitworth JAG, Ruberantwari A, et al Causes and prevalence of non-vision impairing ocular conditions among a rural adult population in SW Uganda Ophthalmic Epidemiol 10.1076/opep.6.1.41.1572
1999 Whitworth J, Pickering H, Mulwanyi F, Ruberantwari A, Dolin P, Johnson G Determinants of attendance and patient satisfaction at eye clinics in south-western Uganda Health Policy Plan 10.1093/heapol/14.1.77
1999 Carpenter LM, Kamali A, Ruberantwari A, Malamba SS, Whitworth JAG Rates of HIV-1 transmission within marriage in rural Uganda in relation to the HIV sero-status of the partners AIDS 10.1097/00002030-199906180-00012
1999 Kamali A, Nunn AJ, Mulder DW, Van Dyck E, Dobbins JG, Whitworth JAG Seroprevalence and incidence of genital ulcer infections in a rural Ugandan population Sex Transm Infect 10.1136/sti.75.2.98
2000 Mbulaiteye SM, Ruberantwari A, Nakiyingi JS, Carpenter LM, Kamali A, Whitworth JAG Alcohol and HIV: a study among sexually active adults in rural south west Uganda Int J Epidemiol 10.1093/ije/29.5.911
2000 Kaleebu P, Whitworth J, Hamilton L, et al Molecular epidemiology of HIV Type 1 in a rural community in southwest Uganda AIDS Res Hum Retroviruses 10.1089/088922200309052
2000 Kamali A, Carpenter LM, Whitworth JAG, Pool R, Ruberantwari A, Ojwiya A Seven-year trends in HIV-1 infection rates, and changes in sexual behaviour among adults in rural Uganda AIDS 10.1097/00002030-200003100-00017
2001 Kaleebu P, Ross A, Morgan D, et al Relationship between HIV-1 Env subtypes A and D and disease progression in a rural Uganda cohort AIDS 10.1097/00002030-200102160-00001
2002 Mbulaiteye SM, Mahe C, Whitworth JAG, et al Declining HIV-1 incidence and associated prevalence over 10 years in a rural population in south-west Uganda: a cohort study Lancet 10.1016/S0140-6736
2002 Mbulaiteye SM, Reeves B, Karabarinde A, et al Evaluation of E optotypes as a screening test and the prevalence and causes of visual loss in a rural population in SW Uganda Ophthalmic Epidemiol 10.1076/opep.9.4.251.1509
2002 Whitworth JAG, Mahe C, Mbulaiteye SM, et al HIV-1 epidemic trends in rural south-west Uganda over a 10 year period Trop Med Int Health 10.1046/j.1365-3156.2002.00973.x
2002 Mbulaiteye SM, Mahe C, Whitworth JAG, Nakiyingi JS, Kamali A HIV-1 incidence and prevalence trends in Uganda Lancet
2002 Yirrell DL, Kaleebu P, Morgan D, et al Inter- and intragenic intersubtype HIV-1 recombination in rural and semi-urban Uganda AIDS 10.1097/00002030-200201250-00018
2003 Nakiyingi JS, Breacher M, Whitworth JAG, et al Child survival in relation to mother’s HIV infection and survival: evidence from a Ugandan cohort study AIDS 10.1097/00002030-200308150-00012
2003 Mbulaiteye SM, Reeves BC, Mulwanyi F, Whitworth JAG, Johnson G Incidence of visual loss in rural southwest Uganda Br J Ophthalmol 10.1136/bjo.87.7.829
2004 Nalweyiso N, Busingye J, Whitworth JAG, Robinson PG Dental treatment needs of children in a rural subcounty of Uganda Int J Paediatr Dent 10.1111/j.1365-263X.2004.00514.x
2004 Yirrell DL, Kaleebu P, Morgan D, Hutchinson S, Whitworth JA HIV-1 subtype dynamics over 10 years in a rural Ugandan cohort Int J STD AIDS 10.1258/095646204322764299
2004 Senkaali D, Muwonge R, Morgan D, Whitworth JAG, Kaleebu P The relationship between HIV-1 disease progression and V3 serotype in a rural Ugandan cohort AIDS Res Hum Retroviruses 10.1089/aid.2004.20.932
2005 Robinson PG, Nalweyiso N, Busingye J, Whitworth JAG Subjective dental impacts of caries and fluorosis in rural Uganda children Community Dent Health
2006 Gale CV, Yirrell DL, Campbell E, Vander Paal L, Grosskurth H, Kaleebu P Genotypic variation in the pol gene of HIV-1 type 1 in an antiretroviral treatment-naïve population in rural southwestern Uganda AIDS Res Hum Retroviruses 10.1089/aid.2006.22.985
2007 Yirrell DL, Wright E, Shafer LA, et al Association between active GBV-C (hepatitis G) infection and HIV-1 disease in Uganda Int J STD AIDS 10.1258/095646207780659006
2007 Biraro S, Morison L, Nakiyingi J, Whitworth JAG, Grosskurth H The role of vertical transmission and health care related factors in HIV infection in children: a community study in rural Uganda J Acquir Immune Defic Syndr 10.1097/QAI.0b013e31802e2954
2008 Shafer LA, Biraro S, Nakiyinji-Miiro J, et al HIV prevalence and incidence are no longer falling in southwest Uganda: evidence from a Rural Population Cohort 1989–2005 AIDS 10.1097/QAD.0b013e32830a7502
2008 Seeley J, Kabunga E, Tumwekwase G, Wolff B, Grosskurth H The impact of the AIDS epidemic on the lives of older people in rural Uganda Working Paper 4
2008 Seeley J, Biraro S, Shafer LA, et al Using in-depth qualitative data to enhance our understanding of quantitative results regarding the impact of HIV and AIDS on households in rural Uganda Soc Sci Med 10.1016/j.socscimed.2008.07.001
2009 Nakibinge S, Maher D, Katende J, Kamali A, Grosskurth H, Seeley J Community engagement in health research: two decades’ experience from a research project on HIV in rural Uganda Trop Med Int Health 10.1111/j.1365-3156.2008.02207.x
2009 Biraro S, Shafer LA, Kleinschmidt I, et al Is sexual behaviour changing in rural southwest Uganda? Behaviour trends in a rural population cohort 1993–2006 Sex Transm Infect 10.1136/sti.2008.033928
2009 Slaymaker E, Bwanika JB, Kasamba I, Lutalo T, Maher D, Todd J Trends in age at first sex in Uganda: evidence from Demographic and Health Survey data, and longitudinal cohorts in Masaka and Rakai Sex Transm Infect 10.1136/sti.2008.034009
2009 Seeley J, Wolff B, Kabunga E, Tumwekwase G, Grosskurth H “And this is where we’ve buried our sons” – the oldest old people coping with the impact of the AIDS epidemic in a resource-poor setting in rural Uganda Ageing Soc
2010 McCarthy M, Maher D, Ly A, Ndip A Developing the agenda for European Union collaboration on non-communicable diseases research in Sub-Saharan Africa Health Res Policy Syst 10.1186/1478-4505-8-13
2010 Maher D, Smeeth L, Sekajugo J Health transition in Africa: practical policy proposals for primary care Bull World Health Organ 10.2471/BLT.10.077891
2010 Nalwoga A, Maher D, Todd J, Karabarinde A, Biraro S, Grosskurth H Nutritional status of children living in a community with high HIV prevalence in rural Uganda: a cross-sectional population based survey Trop Med Int Health 10.1111/j.1365-3156.2010.02476.x
2010 Maher D, Biraro S, Hosegood V, et al Translating global health research aims into action: the example of the ALPHA (Analysing Longitudinal Population-based HIV/AIDS data in Africa) network Trop Med Int Health 10.1111/j.1365-3156.2009.02456.x
2011 Shafer LA, Nsubuga RN, Mayanja BM, et al Antiretroviral therapy and sexual behaviour in Uganda: a cohort study AIDS 10.1097/QAD.0b013e328341fb18
2011 Maher D, Waswa L, Karabarinde A, Baisley K Concurrent sexual partnerships and associated factors: a cross-sectional population-based survey in a rural community in Africa with a generalised HIV epidemic BMC Public Health 10.1186/1471-2458-11-651
2011 Shafer LA, Maher D, Weiss HA, Levin J, Biraro S, Grosskurth H Contribution of population factors to estimation of HIV prevalence trends: a cohort study in rural Uganda, 1989–2007 Am J Epidemiol 10.1093/aje/kwr234
2011 Scholten F, Mugisha J, Seeley J, Zalwango F, Wright S Direct and Indirect Effects of HIV/AIDS and Anti-Retroviral Treatment on the Health and Wellbeing of Older People Geneva: SAGE; WHO
2011 Maher D, Waswa L, Baisley K, Karabarinde A, Unwin N, Grosskurth H Distribution of hyperglycaemia and related cardiovascular disease risk factors in low-income countries: a cross-sectional population-based survey in rural Uganda Int J Epidemiol 10.1093/ije/dyq156
2011 Maher D, Waswa L, Baisley K, Karabarinde A, Unwin N Epidemiology of hypertension in low-income countries: a cross-sectional population-based survey in rural Uganda J Hypertens 10.1097/HJH.0b013e3283466e90
2011 McCreesh N, Johnston LG, Copas A, et al Evaluation of the role of location and distance in recruitment in respondent-driven sampling Int J Health Geogr 10.1186/1476-072X-10-56
2011 Kasamba I, Sully E, Weiss HA, Baisley K, Maher D Extra-spousal partnerships in a community in rural Uganda with high HIV prevalence: a cross-sectional population-based study using linked spousal data J Acquir Immune Defic Syndr 10.1097/QAI.0b013e318227af4d
2011 Scholten F, Mugisha J, Seeley J, et al Health and functional status among older people with HIV/AIDS in Uganda BMC Public Health 10.1186/1471-2458-11-886
2011 Biraro S PhD Thesis: London School of Hygiene and Tropical Medicine; 2011 (Herpes simplex virus type-2: Epidemiological trends and relation with trends in HIV incidence and HIV transmission in south western Uganda) NaN
2011 Maher D, Sekajugo J Research on health transition in Africa: time for action Health Res Policy Syst 10.1186/1478-4505-9-5
2012 Kazooba P, Kasamba I, Baisley K, Mayanja BN, Maher D Access to, and uptake of, ART in a developing country with high HIV incidence: a population-based cohort study in rural Uganda, 2004–2008 Trop Med Int Health 10.1111/j.1365-3156.2012.02942.x
2012 McCreesh N, Nadagire TM, Seeley J, Katongole J, White RG Community understanding of respondent-driven sampling in a medical research setting in Uganda: importance for the use of RDS for public health research Int J Soc Res Methodol 10.1080/13645579.2012.661204
2012 McCreesh N, Frost SD, Seeley J, et al Evaluation of respondent-driven sampling Epidemiology 10.1097/EDE.0b013e31823ac17c
2012 Kasamba I, Baisley K, Mayanja BN, Maher D, Grosskurth H The impact of antiretroviral treatment on mortality trends of HIV-positive adults in rural Uganda: a longitudinal population-based study, 1999–2009 Trop Med Int Health 10.1111/j.1365-3156.2012.02841.x
2013 Murphy GAV; Asiki G; Ekoru K; Nsubuga RN; Nakiyingi-Miiro J; Young EH; Seeley J; Sandhu MS; Kamali A Sociodemographic distribution of non-communicable disease risk factors in rural Uganda: a cross-sectional study International Journal of Epidemiology 10.1093/ije/dyt184
2013 Asiki G, Murphy G, Nakiyingi-Miiro J, Seeley J, Nsubuga RN, Karabarinde A, et al The general population cohort in rural south-western Uganda: a platform for communicable and non-communicable disease studies Int J Epidemiol 10.1093/ije/dys234
2014 Riha J, Karabarinde A, Ssenkusu JM, Allender S, Asiki G, Smeeth L, et al Urbanicity and lifestyle risk factors for cardiometabolic diseases in rural Uganda: a cross-sectional study PLoS Med 10.1371/journal.pmed.1001683
2015 Asiki G; Murphy GAV; Baisley K; Nsubuga RN; Karabarinde A; Newton R; Seeley J; Young EH; Kamali A; Sandhu MS Prevalence of Dyslipidaemia and Associated Risk Factors in a Rural Population in South-Western Uganda: A Community Based Survey PLOS ONE 10.1371/journal.pone.0126166
2016 Asiki G; Reniers G; Newton R; Baisley K; Nakiyingi-Miiro J; Slaymaker E; Kasamba I; Seeley J; Todd J; Kaleebu P; Kamali A Adult life expectancy trends in the era of antiretroviral treatment in rural Uganda (1991–2012) AIDS 10.1097/QAD.0000000000000930
2018 Newton R; Labo N; Wakeham K; Miley W; Asiki G; Johnston WT; Whitby D Kaposi Sarcoma–Associated Herpesvirus in a Rural Ugandan Cohort, 1992–2008 Journal of Infectious Diseases 10.1093/infdis/jix569
2018 Nalwoga A; Miley W; Labo N; et al. Relationship Between Anemia, Malaria Coinfection, and Kaposi Sarcoma–Associated Herpesvirus (KSHV) Seropositivity in Uganda Journal of Infectious Diseases 10.1093/infdis/jiy274
2019 Asiki G; Newton R; Marions L; Kamali A; Smedman L The effect of childhood stunting and wasting on adolescent cardiovascular disease risk and educational achievement in rural Uganda: a retrospective cohort study Global Health Action 10.1080/16549716.2019.1626184
2019 Gurdasani D, Carstensen T, Fatumo S, et al.; Uganda Genome Resource Uganda genome resource enables insights into population history and genomic discovery in Africa Cell 10.1016/j.cell.2019.10.004
2020 Ssemwanga D; Bbosa N; Nsubuga RN; Ssekagiri A; Kapaata A; Nannyonjo M; Nassolo F; Karabarinde A; Mugisha J; Seeley J; Yebra G; Leigh Brown A; Kaleebu P The Molecular Epidemiology and Transmission Dynamics of HIV Type 1 in a General Population Cohort in Uganda Viruses 10.3390/v12111283
2021 Fatumo S; Karhunen V; et al. Discovery and fine-mapping of kidney function loci in first genome-wide association study in Ugandans Human Molecular Genetics 10.1093/hmg/ddab113
2021 Bbosa N; Ssemwanga D; Nsubuga RN; Kiwanuka N; Bagaya BS; Kitayimbwa JM; Ssekagiri A; Yebra G; Kaleebu P; Leigh-Brown A Phylogenetic Networks and Parameters Inferred from HIV Nucleotide Sequences of High-Risk and General Population Groups in Uganda: Implications for Epidemic Control Viruses 10.3390/v13060970
2022 Kalyesubula R; Sekitoleko I; Tomlin K; Hansen C; Ssebunya B; Makanga R; Hughes P; Mbonye MK; Seeley J; Newton R; Tomlinson L Association of impaired kidney function with mortality in rural Uganda: results of a general population cohort study BMJ Open 10.1136/bmjopen-2021-051267
2022 Fatumo S, Wareham NJ, et al.; Uganda Genome Resource (UGR) Uganda Genome Resource: A rich research database for genomic studies of communicable and non-communicable diseases in Africa Cell Genomics
2023 Prynn JE; Davey C; Davis D; Kuper H; Mugisha J; Seeley J Cognition in older adults in Uganda: Correlates, trends over time and association with mortality in prospective population study PLOS Global Public Health
2023 Price AJ; Jobe M; Sekitoleko I; Crampin AC; Prentice AM; Seeley J; Chikumbu EF; Mugisha J; Makanga R; Dube A; Mair FS Epidemiology of multimorbidity in low-income countries of sub-Saharan Africa: Findings from four population cohorts PLOS Global Public Health
2023 Sabourin KR; Mugisha J; Asiki G; Nalwoga A; Labo N; Miley W; Beyer R; Rochford R; Johnston TW; Newton R; Whitby D Epstein–Barr virus (EBV) antibody changes over time in a general population cohort in rural Uganda, 1992–2008 Infectious Agents and Cancer
2023 Sekitoleko I; Nakanga WP; Webb E; Mugamba V; Balungi P; Mpairwe B; Terry O; Makanga R; Nabanoba E; Mugisha JO; Kimbugwe G Identification and characterisation of diabetes in Uganda: protocol for the nested, population-based ‘Diabetes in low-resource Populations’ (DOP) Study BMJ Open
2023 Nalwoga A; Sabourin KR; Miley W; Jackson C; Maktabi M; Labo N; Mugisha J; Whitby D; Rochford R; Newton R Plasmodium falciparum Malaria Is Associated with Increased Kaposi Sarcoma–Associated Herpesvirus (KSHV) Seropositivity and Higher KSHV Antibody Breadth and Magnitude: Results of a Case-Control Study From Rural Uganda The Journal of Infectious Diseases
2023 Mugisha J; Mpairwe B; Newton R; Cotten M; Phan MV SARS-CoV-2 omicron BA.5 infections in vaccinated persons, rural Uganda Emerging Infectious Diseases
2023 Kasamba I, Mugisha J, Abaasa A, Makanga R, Ruzagira E, Kaleebu P, Seeley J, Newton R; Kyamulibwa General Population Cohort team Thirty years of change in HIV incidence among adults in the Kyamulibwa General Population Cohort in rural southwest Uganda, 1989–2021 Int J Infect Dis 10.1016/j.ijid.2023.01.029
2024 Bukenya D; Mpairwe B; Ssentongo JN; Ssenyomo G; Fox J; Newton R; Seeley J; Mugisha JO Experiences of community engagement for SARS‑COV‑2 and COVID‑19 community surveillance in a rural and urban population in South Western Uganda African Health Sciences
2024 Sabourin KR; Marshall VA; Eaton W; Kimono B; Mugisha J; Miley WJ; Labo N; Samayoa-Reyes G; Whitby D; Rochford R; Newton R Factors affecting Kaposi’s sarcoma–associated herpesvirus transmission in rural Ugandan households: a longitudinal study Infectious Agents and Cancer 10.1186/s13027-024-00610-6
2024 Mugisha JO; Makanga R; Kimono BW; Kasamba I Leaving no one behind: Disability and HIV prevention, knowledge among adults in a population cohort in Uganda African Journal of Disability 10.4102/ajod.v13i0.1497
2024 Allan Kalungi, Eugene Kinyanda, Dickens Howard Akena, Bizu Gelaye, Wilber Ssembajjwe, Richard Steven Mpango, Terry Ongaria, Joseph Mugisha, Ronald Makanga, Ayoub Kakande, Beatrice Kimono, Philip Amanyire, Fred Kirumira, Cathryn M. Lewis, Andrew M. McIntosh, Karoline Kuchenbaecker, Moffat Nyirenda, Pontiano Kaleebu, and Segun Fatumo Prevalence and correlates of common mental disorders among participants of the Uganda Genome Resource: Opportunities for psychiatric genetics research Molecular psychiatry
2025 Prynn JE; Alinaitwe R; Kimono B; Peto T; Ashton NJ; Steves CJ; Mugisha J; Prince M Prevalence, aetiology, and service mapping of dementia in rural Uganda. Part of DEPEND Uganda (Dementia Epidemiology, unmet Need and co-Developing Solutions in Uganda) Wellcome Open Research 10.12688/wellcomeopenres.22944.2
2025 Mugisha J, Nalwoga A, Kasamba I, Makanga R, Newton R, et al. Eligibility for hepatitis B virus (HBV) treatment and associated factors in a rural Ugandan population based on 2024 WHO guidelines. medRxiv preprint https://www.medrxiv.org/content/10.1101/2025.04.06.25325341v1