Registration Cohort Results

TABLE 1: DEMOGRAPHIC CHARACTERISTICS

FACTOR

LEVEL

FREQUENCY (%)

(n=4,194)

Age

Median (IQR)

Range

24 (21; 28)

18-45

Sex

Male

Female

693 (16.5%)

3,501 (83. 5%)

Marital status

Single

Married

Cohabiting

 In a relationship but not living together

Widowed

Divorced/separated

2,521 (60.1%)

185 (4.4%)

135 (3.2%)

702 (16.7%)

17 (0.4%)

634 (15.1%)

Education level

No formal education

Incomplete primary

Complete primary

Incomplete secondary

Complete secondary

Technical/vocational school

Complete University/College

Incomplete University/College

91 (2.2%)

704 (16.8%)

1,146 (27.3%)

1,003 (23.9%)

1,080 (25.8%)

62 (1.5%)

61 (1.4%)

47 (1.1%)

Religion

Christian

Muslim

None

Other

2,814 (67.1%)

1,285 (30.6%)

85 (2.0%)

10 (0.2%)

Occupation

Professional/technical worker

Office clerk

Sales/service worker

Subsistence agricultural worker

Subsistence fisheries worker

Craft and related trades worker

Armed forces/security services

House helper/labourer

Salon/lodge/bar worker, market/street vendor

Sex worker

Unemployed

Other

130 (3.1%)

16 (0.4%)

249 (5.9%)

119 (2.8%)

106 (2.5%)

80 (1.9%)

14 (0.3%)

133 (3.2%)

1,410 (33.6%)

2,403 (57.3%)

598 (14.3%)

183 (4.4%)

Source of income

Formal employment

Self-employment

Casual labour

Family

Spouse/boyfriend/girlfriend

Sex work

None

Other

165 (3.9%)

611 (14.6%)

1,380 (32.9%)

242 (5.8%)

519 (12.4%)

2,418 (57.6%)

168 (4.0%)

232 (5.5%)

Number of children under the age of 18 who live in your household

Median (IQR)

Range

1 (0; 2)

0-14

The number of people who are financially dependent on you

Median (IQR)

Range

2 (1; 3)

0-30

Number of people, including you that live in your household

Median (IQR)

Range

3 (2; 5)

1-34

How many rooms in your household are used for sleeping

Median (IQR)

Range

1 (1; 3)

0-13

Do you have electricity in your household?

No

Yes

1,069 (25.5%)

3,125 (74.5%)

What is the main source of drinking water for your household

Piped into dwelling

Piped into yard/plot

Public tap/standpipe

Borehole

Protected dug well

Unprotected dug well

Protected spring

Unprotected spring

Collected rainwater

Bottled water

Tanker-truck

Surface water (river/stream/lake/dam/pond)

Other

404 (9.6%)

1,411 (33.6%)

1,781 (42.5%)

160 (3.8%)

57 (1.4%)

119 (2.8%)

35 (0.8%)

18 (0.4%)

8 (0.2%)

120 (2.9%)

24 (0.6%)

43 (1.0%)

14 (0.3%)

Pregnancy status

(n=3,501)

Positive

Negative

151 (4.3%)

3,350 (95.7%)

 

Table 2: Incidence of HIV infections.

Factor

Person-time (N)

n

Rate (95% CI)

HIV infections

4023.9233

111

2.75% (2.29%; 3.32%)

 

Table 3: Secondary outcomes

Outcome

Level

Frequency (%)

(n=4,194)

PrEP knowledge

No

Yes

1,741 (41.5%)

2,453 (58.5%)

PrEP Uptake

(n=2,453)

Not currently using

Currently using

2,424 (98.8%)

29 (1.2%)

Willingness to use PrEP if offered

No

Yes

Not sure

228 (5.4%)

3,774 (90.0%)

192 (4.6%)

 

PrEP adherence

Ever initiated PrEP

No

Yes

3,930 (93.7%)

264 (6.3%%)

Remained on PrEP throughout follow-up

(n=264) 

– yes

113 (42.8%)

Ever discontinued PrEP

(n=264) 

– yes

151 (57.2%)

Median visits to discontinuation (IQR)* 

 

1 (1–2)

Mean visits to discontinuation (SD)*

 

1.5 (0.8)

*Visits to discontinuation counted from the initiation visit.

 

Table 4: Risky sex Behaviour & Reproductive health factors.

FACTOR

LEVEL

Frequency (%)

(n=4,194)

When did you last have sex

≤ 1 week

3,349 (79.9%)

 

>1 to ≤4 weeks

701 (16.7%)

 

>4 weeks to ≤3 months

136 (3.2%)

 

>3 months

8 (0.2%)

Used a condom at last sex

No

3,140 (74.9%)

 

Yes

1,050 (25%)

 

Not sure

4 (0.1%)

Last sex without a condom (among those who used a condom at last sex, n=1,050)

≤ 1 week ago

374 (35.6%)

>1 to ≤4 weeks ago

413 (39.3%)

>4 weeks to ≤3 months ago

145 (13.8%)

>3 months ago

118 (11.2%)

Number of sexual partners in the last 3 months

 

Total sex partners

Median (IQR)

9 ((3–45)%)

Partners without a condom

Median (IQR)

4 ((2–15)%)

New sexual partners

Median (IQR)

4 ((1–18)%)

New partners without a condom

Median (IQR)

3 ((1–9)%)

Exchanged sex for money, gifts, or favours (last 3 months)

No

827 (19.8%)

Yes — received

3,053 (72.9%)

Yes — given

266 (6.4%)

Yes — both

40 (1%)

Condom use during transactional sex (n=3,359)

Never used a condom

824 (24.5%)

Sometimes

2,381 (70.9%)

Always

154 (4.6%)

Sex with person of unknown HIV status

No

280 (6.7%)

Yes

3,906 (93.3%)

No. of partners with unknown HIV status (n=3,906)

 

Median (IQR)

9 ((3–50)%)

Condom use with HIV-unknown partners (n=3,906)

Never used a condom

920 (23.6%)

Sometimes

2,774 (71%)

Always

212 (5.4%)

Sex with an HIV-infected person

No

455 (10.9%)

Yes

135 (3.2%)

Don’t know

3,596 (85.9%)

Sex with partner ≥10 years older

No

1,377 (32.9%)

Yes

2,737 (65.4%)

Not sure

72 (1.7%)

Partner(s) have other sexual partners

No

104 (2.5%)

Yes

3,433 (82%)

Not sure

221 (5.3%)

Don’t know

428 (10.2%)

Had sex when did not want to (unwilling)

No

1,398 (33.4%)

Yes

2,788 (66.6%)

Had sex when felt pressurised

 

No

1,582 (37.8%)

Yes

2,604 (62.2%)

Had sex when physically forced

No

3,674 (87.8%)

Yes

512 (12.2%)

Ever had anal sex with other men  (n=693)

No

642 (92.6%)

Yes

51 (7.4%)

Anal sex with men in last 3 months (n=51)

No

11 (21.6%)

Yes

40 (78.4%)

Condom use during anal sex with men

(n=40)

Never used a condom

8 (20%)

Sometimes

23 (57.5%)

Always

9 (22.5%)

In the last 3 months, have you had any abnormal genital discharge

No

Yes

Not sure

3,102 (74.0%)

1,083 (25.8%)

9 (0.2%)

If yes, when was the last time you had abnormal genital discharge

<= 1 week

>1 to <=4 weeks

>4 weeks to <=3 months

347 (32.0%)

350 (32.3%)

386 (35.6%)

In the last 3 months, have you had genital sores or ulcers

No

Yes

Not sure

3,694 (88.1%)

479 (11.4%)

21 (0.5%)

If yes, when was the last time you had genital sores or ulcers

<= 1 week

>1 to <=4 weeks

>4 weeks to <=3 months

117 (24.4%)

168 (35.1%)

194 (40.5%)

In the last 3 months, have you been diagnosed with or received treatment for a sexually transmitted infection?

 

No

Yes

Not sure

3,424 (81.6%)

729 (17.4%)

41 (1.0%)

If yes, when was the last time you were diagnosed with or received treatment for a sexually transmitted infection? 

<= 1 week

>1 to <=4 weeks

>4 weeks to <=3 months

93 (12.8%)

266 (36.5%)

370 (50.7%)

In the last 3 months, has your partner been diagnosed with or received treatment for a sexually transmitted infection?

 

No

Yes

Not sure

830 (19.8%)

211 (5.0%)

3,153 (75.2%)

If yes, when was the last time your partner was diagnosed with or received treatment for a sexually transmitted infection? 

<= 1 week

>1 to <=4 weeks

>4 weeks to <=3 months

13 (6.2%)

79 (37.4%)

119 (56.4%)

Have you used any recreational drugs (i.e. chemical substances taken for enjoyment, or leisure purposes, rather than for medical reasons) in the past 3 months? 

No

Yes

3,580 (85.4%)

614 (14.6%)

If yes, how often did you have sex after using recreational drugs?

 

Never

Sometimes (<50% of the time)

Frequently (>50% of the time)

Always

58 (9.4%)

341 (55.5%)

149 (24.3%)

66 (10.7%)

In the last 3 months, how often did you have a drink containing alcohol?

Never

Once a month or less

2-4 times a month

2-3 times a week

4 or more times a week

950 (22.6%)

322 (7.7%)

610 (14.5%)

1,140 (27.2%)

1,172 (27.8%)

How often did you get drunk after having an alcoholic drink?

Never

Sometimes (<50% of the time)

Frequently (>50% of the time)

Always

439 ()

1,898 ()

634 (19.5%)

273 (8.4%)

How often did you have sex when drunk?

Never

Sometimes (<50% of the time)

Frequently (>50% of the time)

Always

273 (9.7%)

1,725 (61.5%)

512 (18.2%)

295 (10.5%)

Are you circumcised?

(n=693)

No

Yes

142 (20.5%)

551 (79.5%)

Are you currently using any contraceptive method?

(n=3,501)

 

No

Yes

NA

1,248 (35.6%)

2,253 (64.4%)

What methods of contraception?

Oral contraceptives

Transdermal patch

Injectable-DMPA contraceptives

Injectable-NET-EN

Injectable-combined progestin-oestrogen

Implant

Intrauterine device

Surgical sterilisation

Male condoms

Female condoms

Spermicides

Other

183 (8.1%)

35 (1.6%)

873 (38.7%)

111 (4.9%)

41 (1.8%)

 

718 (31.9%)

69 (3.1%)

14 (0.6%)

265 (11.8%)

9 (0.4%)

38 (1.75)