Entebbe Cohort EVCA

Vital Sign

N

Mean (SD)

Temperature (°C)

1,568

38.2 (0.8)

Respiratory rate (/min)

1,531

25.9 (8.8)

Pulse (/min)

1,550

97.6 (18.1)

Weight (kg)

206

57.3 (13.5)

Systolic BP (mmHg)

330

104.0 (12.9)

Diastolic BP (mmHg)

330

65.1 (10.0)

Symptom

S1 n (%)

N=1,575

S2 n (%)

N=1,443

S3 n (%)

N=1,121

S4 n (%)

N=768

Fever

1,005 (63.8%)

252 (17.5%)

79 (7.1%)

4 (0.5%)

Cough

240 (15.2%)

350 (24.3%)

126 (11.2%)

40 (5.2%)

Headache

62 (3.9%)

235 (16.3%)

118 (10.5%)

33 (4.3%)

Diarrhoea

41 (2.6%)

112 (7.8%)

104 (9.3%)

36 (4.7%)

Rash

29 (1.8%)

—

—

—

Joint pain

27 (1.7%)

54 (3.7%)

46 (4.1%)

19 (2.5%)

Vomiting

18 (1.1%)

—

—

—

Abdominal pain

18 (1.1%)

40 (2.8%)

46 (4.1%)

25 (3.3%)

Eye problem

—

55 (3.8%)

76 (6.8%)

23 (3.0%)

Sore mouth

—

—

—

23 (3.0%)

Other

38 (2.4%)

70 (4.9%)

98 (8.7%)

51 (6.6%)

Examination Finding

Level

n (%)

General Examination

Wasting (n = 332)

Yes

65 (19.6%)

Anaemia (n = 333)

Yes

36 (10.8%)

Oedema (n = 333)

Yes

17 (5.1%)

Weakness (n = 332)

Yes

133 (40.1%)

Jaundice (n = 333)

Yes

3 (0.9%)

Lymphadenopathy (n = 209)

Yes

33 (15.8%)

General impression: Healthy (n = 317)

Yes

52 (16.4%)

General impression: Moderately ill (n = 317)

Yes

225 (71.0%)

General impression: Severely ill (n = 317)

Yes

40 (12.6%)

Skin & Mucocutaneous

Any skin finding (n = 327)

Yes

92 (28.1%)

Any mucocutaneous finding (n = 324)

Yes

86 (26.5%)

  Oral candidiasis (n = 324)

Yes

45 (13.9%)

  Angular cheilitis (n = 324)

Yes

13 (4.0%)

  Herpes labialis (n = 324)

Yes

5 (1.5%)

  Hairy leukoplakia (n = 324)

Yes

5 (1.5%)

  Kaposi sarcoma (skin) (n = 324)

Yes

4 (1.2%)

  Other mucocutaneous (n = 324)

Yes

7 (2.2%)

Respiratory System

Any respiratory sign (rs1) (n = 1,553)

Yes

337 (21.7%)

  Cough (sign) (n = 1,553)

Yes

134 (8.6%)

  Crepitations (n = 1,553)

Yes

57 (3.7%)

  Wheeze (n = 1,553)

Yes

27 (1.7%)

  Rhonchi (n = 1,553)

Yes

18 (1.2%)

  Other respiratory sign (n = 1,553)

Yes

93 (6.0%)

Pneumonia (n = 210)

Yes

40 (19.0%)

Bronchitis (n = 185)

Yes

16 (8.6%)

Bronchial obstruction (n = 182)

Yes

2 (1.1%)

Pleural effusion (n = 183)

Yes

2 (1.1%)

Cardiovascular System

Murmurs (n = 331)

Yes

2 (0.6%)

Cardiomegaly (n = 1,567)

Yes

45 (2.9%)

Abdomen

Hepatomegaly (n = 1,574)

Yes

140 (8.9%)

Splenomegaly (n = 1,570)

Yes

141 (9.0%)

Abdominal tenderness (n = 332)

Yes

48 (14.5%)

Ascites (n = 333)

Yes

3 (0.9%)

Other abdominal finding (n = 1,574)

Yes

168 (10.7%)

Central Nervous System

Any CNS abnormality (n = 1,574)

Yes

49 (3.1%)

Gait abnormality (n = 127)

Yes

2 (1.6%)

Mental state abnormal (n = 129)

Yes

2 (1.6%)

Speech abnormality (n = 127)

Yes

2 (1.6%)

Meningeal signs (n = 127)

Yes

2 (1.6%)

Disturbed vision (n = 127)

Yes

1 (0.8%)

Retinal abnormality (n = 126)

Yes

1 (0.8%)

Motor deficit (n = 127)

Yes

0 (0.0%)

Tremor (n = 127)

Yes

0 (0.0%)

Sensory deficit (n = 127)

Yes

0 (0.0%)

Pupil abnormality (n = 127)

Yes

0 (0.0%)

Cranial nerve deficit (n = 127)

Yes

0 (0.0%)

Babinski positive (n = 127)

Yes

0 (0.0%)

LP performed (n = 127)

Yes

0 (0.0%)

Genito-Urinary System

Any GUS abnormality (n = 332)

Yes

13 (3.9%)

Urethral/vaginal discharge (n = 134)

Yes

7 (5.2%)

Genital lesions (n = 135)

Yes

7 (5.2%)

WHO Clinical Stage (n = 164)

Stage 1

8 (4.9%)

Stage 2

78 (47.6%)

Stage 3

54 (32.9%)

Stage 4

24 (14.6%)

Management & Outcome

Treatment given (n = 331)

Yes

328 (99.1%)

Referred (n = 320)

Yes

63 (19.7%)

Outcome (n = 1,566)

Improved

1,204 (76.9%)

Unchanged

99 (6.3%)

Worsened

226 (14.4%)

Died

37 (2.4%)